Manganese Gluconate

    • Product Name: Manganese Gluconate
    • Chemical Name (IUPAC): Manganese(II) bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
    • CAS No.: 6485-39-8
    • Chemical Formula: C12H22MnO14
    • Form/Physical State: Solid
    • Factroy Site: No.1202, Fangshan Road,Changle County,Weifang, Shandong, China
    • Price Inquiry: sales2@boxa-chem.com
    • Manufacturer: Weifang Shengtai Medicine Co.,Ltd.
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    Specifications

    HS Code

    293267

    Chemical Name Manganese Gluconate
    Molecular Formula C12H22MnO14
    Molecular Weight 445.25 g/mol
    Appearance Light pink to pinkish-tan powder
    Solubility In Water Freely soluble
    Melting Point Decomposes
    Cas Number 6485-39-8
    Stability Stable under normal conditions
    Odor Odorless
    Storage Conditions Store in a cool, dry place, tightly closed
    Ph Of 1 Percent Solution 5.0 – 7.5
    Uses Nutritional supplement, food fortification, pharmaceutical ingredient

    As an accredited Manganese Gluconate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Manganese Gluconate, 1 kg, securely sealed in a white HDPE plastic bottle with tamper-evident cap, labeled with product details.
    Container Loading (20′ FCL) Manganese Gluconate is packed in 25kg drums or bags; a 20′ FCL contains approximately 10 metric tons securely loaded.
    Shipping Manganese Gluconate is shipped in tightly sealed containers, typically made of HDPE, to prevent moisture absorption and contamination. Packages must be clearly labeled, handled with care, and stored in a cool, dry place. Transport should comply with local regulations and best practices for non-hazardous, non-flammable, and non-toxic chemicals.
    Storage Manganese Gluconate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat and moisture. Protect it from light and incompatible substances such as strong acids and oxidizing agents. Store at room temperature, ideally between 15°C and 30°C (59°F to 86°F), and keep out of reach of children and unauthorized personnel.
    Shelf Life Manganese Gluconate typically has a shelf life of 2 to 3 years when stored in a cool, dry, and sealed container.
    Application of Manganese Gluconate

    Purity 98%: Manganese Gluconate with purity 98% is used in pharmaceutical formulations, where it ensures high bioavailability and effective manganese supplementation.

    Molecular Weight 445.3 g/mol: Manganese Gluconate with molecular weight 445.3 g/mol is used in dietary supplements, where precise dosing and consistent trace mineral delivery are achieved.

    Particle Size D90 < 150 µm: Manganese Gluconate with particle size D90 less than 150 µm is used in premix blends for animal nutrition, where homogenous distribution improves feed efficacy.

    Solubility in Water > 200 g/L: Manganese Gluconate with water solubility greater than 200 g/L is used in liquid multivitamin preparations, where rapid dissolution enhances formulation clarity.

    Stability Temperature up to 60°C: Manganese Gluconate stable up to 60°C is used in processed food fortification, where it maintains mineral integrity during thermal processing.

    pH Range 4.0-6.5: Manganese Gluconate with pH range 4.0 to 6.5 is used in beverage enrichment, where stability in acidic solutions supports shelf-life.

    Loss on Drying < 6.0%: Manganese Gluconate with loss on drying below 6.0% is used in nutritional tablets, where low moisture content extends product stability.

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    Certification & Compliance
    More Introduction

    Manganese Gluconate: A Closer Look from the Manufacturer's Perspective

    Understanding Manganese Gluconate

    Manganese Gluconate holds a unique position among trace mineral supplements and food additives. In our experience as producers, this compound combines strong solubility with mild taste and reliable stability. Manganese Gluconate stands out from other manganese salts, such as sulfate or chloride, due to its high bioavailability and gentle profile. The fumaric and citric acid chelates can compete in specialty applications, but gluconate manages a superior track record in nutraceutical and food industries, thanks to its clean label reputation and ease of formulation.

    Our Model and Key Specifications

    We manufacture Manganese Gluconate with high purity in mind. Our primary product typically features an assay of over 98% as C12H22MnO14, which meets or exceeds quality grades common to major global markets. Consistent appearance confirms quality: a pale yellow or off-white powder, flowing readily for accurate dosing. Moisture content stays low, below the recognized 9% mark, retaining product flow and shelf life. Our batches pass stringent checks for heavy metals, lead, and arsenic, building buyer confidence in long-term partnerships. Particle size variation draws from input by end users, mostly settling around 40 to 100 mesh, which works for both tablet compaction and powder blends. The melting point, typically overlooked, remains above 120°C; this helps minimize deterioration during standard processing.

    Real-World Uses That Matter

    We have supplied Manganese Gluconate to customers who create vitamin and mineral tablets, effervescent blends, and even beverage fortifiers. Its chief attraction comes from the element’s role in activating enzymes involved with metabolism, bone formation, and antioxidant defense. The gluconate form dissolves with very little residue, and the profile stays relatively neutral in finished products, so beverage and nutrition companies turn to it over metallic-tasting options. As demand grows for plant-based foods and functional beverages, we have seen usage expand into bakery mixes, sports nutrition, and infant formulas. Powdered meal replacements, breakfast cereals, and liquid supplements also benefit from gluconate’s mild palate impact and easy dispersibility.

    Agricultural and animal nutrition sectors look at manganese for animal feed to address trace mineral deficiencies. Here, solubility and absorption rate matter, especially for poultry and swine. We pay careful attention to impurity profiles and particle sizing to serve these clients, ensuring the mineral does not clump or settle out of premixes. Sometimes clients ask about fertilizer applications. While manganese gluconate can supply plants in foliar sprays, it does not always match the economic efficiency found in industrial manganese sulfate. Still, for applications sensitive to environmental residues, such as hydroponics or organically inclined practices, the gluconate option has merit.

    How Manganese Gluconate Compares to Alternatives

    For those seeking a straightforward source of elemental manganese, several forms are available. Manganese sulfate, chloride, and carbonate all provide manganese, but each brings drawbacks for specific uses. Sulfate carries a strong aftertaste in food and can add undesirable sodium or potassium. Manganese chloride dissolves well yet offers less stability and can impart bitterness. Manganese carbonate ranks lowest in solubility and brings poor taste masking. In food, beverage, and dietary supplement settings, these attributes often lead formulators to gluconate.

    Chelated forms such as manganese bisglycinate or ascorbate appear in specialty premium supplements, offering enhanced absorption but at higher cost and sometimes requiring novel regulatory assessments. Our clients who choose gluconate typically cite its combination of affordability, handling characteristics, safety record, and regulatory acceptance as their top criteria. Pharmaceutical and nutritional firms in both North America and Europe trust gluconate’s track record, pointing to its long GRAS (Generally Recognized as Safe) status in the US and positive monographs in EP, USP, and FCC compendia. We continue to update quality systems to maintain alignment with these references.

    Safety, Purity, and Transparency in Manufacturing

    Few things matter more to a chemical producer than rigorous quality control. Trace mineral ingredients go into products consumed by millions of people worldwide; the smallest impurity can become a headline. We take particular pride in our purification process for Manganese Gluconate, eliminating the sources of heavy metals and organic contaminants before any batch leaves the plant. Our plant operates with closed-system reactors to dodge cross-contamination. Routine audits and skilled personnel check for batch-to-batch consistency. Each production lot receives a certificate showing assay, solubility, moisture content, appearance, and heavy metal results.

    You rarely see adverse events linked to manganese gluconate in properly labeled supplements. Most clinical studies confirm tolerability when used within recommended dietary limits, which for adults sits at 1.8-2.3 mg manganese daily from all sources. Gluconate form’s safety record makes it an obvious choice for manufacturers who want to reduce recall risk. Our long-term relationships rest on being upfront about analytical methods, test results, and supply chain origins. We invest heavily in traceability—every drum, carton, and inner bag carries batch codes, tracking production all the way back to raw ore and glucose processing.

    Sourcing and Sustainability Commitments

    We draw our manganese from well-documented, responsibly mined ore. Over the years, we have worked with suppliers who know our standards and understand the global push for traceability. Industrial glucose, the organic acid base, often hails from non-GMO corn or tapioca. Meeting rising demand for non-allergenic, vegan-friendly ingredients, our facility avoids any animal-based process aids, enrolling Manganese Gluconate in recognized vegan certification programs.

    Waste minimization runs through our entire operation. The gluconate reaction captures and recycles solvents, so water use drops over time. Byproducts such as spent filter cake return to partner sites for further metal recovery or safe neutralization. We continually update emissions controls to meet both local and international environmental expectations. Voluntary audits, not just mandated ones, keep pressure on us to stay ahead of evolving sustainability targets. Every year, our eager new hires bring ideas for reducing energy use per kilogram produced; sometimes a well-placed sensor pays off better than a total overhaul.

    Serving the Food and Supplement Industries

    Research and development teams from nutraceutical, functional food, and beverage companies rely on Manganese Gluconate in their ingredient toolkits. The challenge often comes in achieving the right balance between taste neutrality and nutritional boost. Having produced this material for more than a decade, we've seen reformulations in all sorts of products: chewable tablets, sports drinks, powders, and gummies. Supplement marketers increasingly prefer fortification forms that don’t disrupt taste or mouthfeel; gluconate delivers here by being practically flavorless and nearly odorless. Blending it with vitamins, other minerals, and botanicals rarely causes caking or separation issues.

    One point of pride is seeing more plant-based and allergen-free foods make use of our manganese. As consumer concerns around clean labels and minimal additives rise, formulators steer away from traditional salt forms with off notes or allergens. Our technical service team often helps customers dial in the right inclusion rate for label claims: for beverage fortification, they want rapid dispersion and no visible particles, while for capsule and tablet manufacturers, ease of compaction and flowability are key. We learn by seeing what challenges arise, sometimes modifying particle size distributions or adjusting drying profiles to help downstream processing.

    Potential Issues: Handling and Formulation Tips

    With all mineral salts, storage and handling conditions can impact shelf life and user experience. We ship Manganese Gluconate in double-lined bags and fiber drums, and we always load containers in dry, cool environments. Once opened, the product fares best in airtight containers, away from humidity which can invite clumping. Some customers have automation lines set up for larger mesh sizes, but fine grades can create dust if improperly managed. Our advice: transfer powders slowly, with local exhaust if possible, and schedule regular feeder checks.

    Our tech team gets regular questions about compatibility and stability. Acidic beverages, for example, present little challenge—the gluconate anion keeps the manganese in a soluble, ready-to-absorb form over broad pH levels. In tablet blends, some excipients like magnesium stearate can slow dissolution; careful mix sequencing resolves this. Granulated forms, which we offer on request, provide better flow in sachet filling lines. If a customer wants to add colorants or botanicals, we suggest pre-mixing with a carrier to disperse evenly. Most troubleshooting leads back to finding the right sequence in blending, not reinventing the ingredient.

    Meeting Industry and Regulatory Standards

    Nothing matters more to manufacturers or brands than confidence in regulatory compliance. Our Manganese Gluconate aligns with USP, EP, and FCC specifications, which gives our customers an easier path for new product registration across North America, Europe, and Asia-Pacific. Regional regulations differ, but familiarity with purity, labeling, and contaminant thresholds helps prevent issues. We handle all documentation for health authorities, including full specification sheets, heavy metal analyses, and retest intervals. Our lot numbering system matches with Good Manufacturing Practice (GMP) guidance, making tracebacks fast and avoiding supply disruptions.

    We see global regulatory interests shifting towards greater transparency in the full production process. Customers now request allergen-free, non-GMO, kosher, and halal declarations at a higher rate. We keep all such records on file and can share them with partners for audit purposes. Occasionally, a client may need special analysis for dioxins or persistent organic pollutants depending on region; we handle coordination with certified labs for these requests.

    Technology and Innovation in Production

    Producing mineral gluconates draws on both chemistry expertise and experience in plant optimization. We begin with manganese carbonate or oxide, reacting with gluconic acid from glucose fermentation. Catalysts and reaction vessels affect yield, and we continually tweak conditions to minimize impurities. Over the years, our process control has advanced, using in-line spectroscopy and real-time assay adjustments. Investing in process analytical technology (PAT) means we catch variability as it starts, not at the end of a batch. This helps us tighten specifications and pass savings to customers.

    Our staff participate in peer-reviewed research projects and maintain ties to university chemists exploring improved chelation methods. Process scale-up often brings new problems, such as managing exothermic reaction steps without losing yield or product color. One way we manage energy costs involves recovering low-grade steam from cooling loops to run other plant utilities. Teams collaborate in problem-solving sessions, often yielding practical changes like new filter designs or more effective mother liquor separation, cutting back both waste and reprocessing costs.

    Why Consistency Matters

    With essential minerals, every dose must deliver on label claims—no more, no less. Process drift, a familiar problem in chemical operations, undermines trust. One batch running outside assay range can end up scrapped, which burns both resources and reputations. Our investment in automated weigh stations and robotics for charging and discharge has cut those deviations to less than 0.1%. Sample records, both paper and digital, stay archived for over a decade, ready for inspection or historical review.

    Customers buying a mineral supplement ingredient expect reliability: that today’s lot will match next month’s. Our own quality personnel take nothing for granted, running duplicate checks on key parameters. Regular reviews, internal and external, catch trends before they become issues. Trust builds over years; one error can shake it. We recognize this, and our shop floor staff receive regular training in both cGMP and cross-department troubleshooting. Often suggestions for incremental improvements come straight from operators who notice color drifts or smell changes before a lab report flags them.

    Supporting Customers in Application Development

    Buying a high-quality Manganese Gluconate is only half the equation. Our technical team works closely with customers to fine-tune incorporation into new blends, pilot batches, or scaled production. We spend time reviewing each application’s needs: whether the demand centers on flow properties, quick dissolving, low dust, or minimal taste. We often conduct side-by-side evaluations with other manganese forms to demonstrate gluconate’s convenience in final products.

    Real-world technical support pays off when customers encounter unique challenges. From unexpected caking in a vitamin powder blend to questions about color development in protein shakes, our specialists tackle the issue with data and hands-on advice. Customers trust us with confidential trials and proprietary finished product details—something we take seriously. Frequent feedback loops give us a front-row seat for trends and new expectations, so we can adapt future production accordingly.

    Looking Ahead: Anticipating Change in the Marketplace

    The landscape for trace mineral ingredients evolves quickly. Manufacturers face rising scrutiny over source, safety, and sustainability. We see demand shifting not just toward higher quality, but toward more transparency and environmental responsibility. As a primary manufacturer, we must anticipate these changes, not simply respond to them. Investments in supply chain mapping, real-time environmental monitoring, and digital batch records are paying off as customers push for open-data and block-chain style tracking.

    Emerging trends point to sharper consumer awareness about bioavailability and the differences between what a label claims and what an ingredient delivers. Manganese Gluconate finds itself well positioned in this regard: its absorption characteristics and low side-effect profile continue to win favor. Food and supplement formulators will keep looking for clean, cost-effective, and regulatory-friendly mineral options. Our role is to listen, innovate, and support reliably—not just as producers, but as partners invested in customer and consumer success.